MBV embedded within the extracellular matrix of heart tissue (false colored blue)
MBV embedded within the extracellular matrix of heart tissue (false colored blue)

Research

The Dewey Lab engineers cellular signals for regenerative medicine. We combine biomaterials with extracellular vesicles, which are nano-sized lipid encapsulated cargo secreted by cells for cell-signaling purposes. Specifically, we focus much of our effort on the understanding and application of a new class of extracellular vesicle in regenerative medicine, a type of vesicle found residing in the extracellular matrix termed matrix-bound nanovesicles (MBV). Below, you can find links to the various projects ongoing in the laboratory.